JBMRThe American Society for Bone and Mineral Research


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Parathyroid Hormone (PTH) Articles



Building bone with a SOST-PTH partnership
Natalie A Sims

Parathyroid hormone regulates fetal‐placental mineral homeostasis
Charlene S Simmonds, Gerard Karsenty, Andrew C Karaplis, Christopher S Kovacs

The role of mast cells in parathyroid bone disease
Russell T Turner, Urszula T Iwaniec, Kevin Marley, Jean D Sibonga

Elevated serum IGF-1 levels synergize PTH action on the skeleton only when the tissue IGF‐1 axis is intact
Sebastien Elis, Hayden‐William Courtland, Yingjie Wu, J Christopher Fritton, Hui Sun, Clifford J Rosen, Shoshana Yakar

Increased osteocyte death and mineralization inside bone after parathyroidectomy in patients with secondary hyperparathyroidism
Aiji Yajima, Masaaki Inaba, Yoshihiro Tominaga, Yoshiki Nishizawa, Kyoji Ikeda, Akemi Ito

Early-onset, progressive, frequent, extensive, and severe bone mineral and renal complications in multiple endocrine neoplasia type 1–associated primary hyperparathyroidism
Delmar M Lourenço, Flavia L Coutinho, Rodrigo A Toledo, Fabio LM Montenegro, Joya EM Correia‐Deur, Sergio PA Toledo

Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms
Robert L Jilka, Charles A O'Brien, Shoshana M Bartell, Robert S Weinstein, Stavros C Manolagas

Tissue-specific regulatory regions of the PTH gene localized by novel chromosome 11 rearrangement breakpoints in a parathyroid adenoma
Sanjay M Mallya, H Irene Wu, Elizabeth A Saria, Kristin R Corrado, Andrew Arnold

Impact of race on hyperparathyroidism, mineral disarrays, administered vitamin D mimetic, and survival in hemodialysis patients
Kamyar Kalantar‐Zadeh, Jessica E Miller, Csaba P Kovesdy, Rajnish Mehrotra, Lilia R Lukowsky, Elani Streja, Joni Ricks, Jennie Jing, Allen R Nissenson, Sander Greenland, Keith C Norris

Effects of intravenous zoledronic acid plus subcutaneous teriparatide [rhPTH(1–34)] in postmenopausal osteoporosis
Felicia Cosman, Erik Fink Eriksen, Chris Recknor, Paul D Miller, Núria Guañabens, Christian Kasperk, Philemon Papanastasiou, Aimee Readie, Hanumantha Rao, Jürg A Gasser, Christina Bucci‐Rechtweg, Steven Boonen

Differential effects of teriparatide on regional bone formation using 18 F-fluoride positron emission tomography
Michelle L Frost, Musib Siddique, Glen M Blake, Amelia EB Moore, Paul J Schleyer, Joel T Dunn, Edward J Somer, Paul K Marsden, Richard Eastell, Ignac Fogelman

PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling
Yumie Rhee, Matthew R Allen, Keith Condon, Virginia Lezcano, Ana C Ronda, Carlo Galli, Naomi Olivos, Giovanni Passeri, Charles A O'Brien, Nicoletta Bivi, Lilian I Plotkin, Teresita Bellido

The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates
Lei Shu, Ji Ji, Qi Zhu, Guofan Cao, Andrew Karaplis, Martin R Pollak, Edward Brown, David Goltzman, Dengshun Miao

Parathyroid hormone regulates the distribution and osteoclastogenic potential of hematopoietic progenitors in the bone marrow
Christian E Jacome‐Galarza, Sun‐Kyeong Lee, Joseph A Lorenzo, Hector Leonardo Aguila

FGF-23/Klotho signaling is not essential for the phosphaturic and anabolic functions of PTH
Quan Yuan, Tadatoshi Sato, Michael Densmore, Hiroaki Saito, Christiane Schüler, Reinhold G Erben, Beate Lanske

A 7-day continuous infusion of PTH or PTHrP suppresses bone formation and uncouples bone turnover
Mara J Horwitz, Mary Beth Tedesco, Susan M Sereika, Linda Prebehala, Caren M Gundberg, Bruce W Hollis, Alessandro Bisello, Adolfo Garcia‐Ocaña, Raquel M Carneiro, Andrew F Stewart

Hypoparathyroidism in the adult: Epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research
John P Bilezikian, Aliya Khan, John T Potts, Maria Luisa Brandi, Bart L Clarke, Dolores Shoback, Harald Jüppner, Pierre D'Amour, John Fox, Lars Rejnmark, Leif Mosekilde, Mishaela R Rubin, David Dempster, Rachel Gafni, Michael T Collins, Jim Sliney, James Sanders

The effect of adding PTH(1–84) to conventional treatment of hypoparathyroidism: A randomized, placebo-controlled study
Tanja Sikjaer, Lars Rejnmark, Lars Rolighed, Lene Heickendorff, Leif Mosekilde,

Parathyroid hormone signaling via Gαs is selectively inhibited by an NH 2 -terminally truncated Gαs: Implications for pseudohypoparathyroidism
Svetlana Puzhko, Cynthia Gates Goodyer, Mohammad Amin Kerachian, Lucie Canaff, Madhusmita Misra, Harald Jüppner, Murat Bastepe, Geoffrey N Hendy

Skeletal anabolism, PTH, and the bone–vascular axis
Dwight A Towler

Intermittent PTH(1–84) is osteoanabolic but not osteoangiogenic and relocates bone marrow blood vessels closer to bone-forming sites
Rhonda Prisby, Alain Guignandon, Arnaud Vanden‐Bossche, Fabrice Mac‐Way, Marie‐Thérèse Linossier, Mireille Thomas, Norbert Laroche, Luc Malaval, Max Langer, Zoltz‐Andrei Peter, Françoise Peyrin, Laurence Vico, Marie‐Hélène Lafage‐Proust

PTH(1–84) administration reverses abnormal bone-remodeling dynamics and structure in hypoparathyroidism
Mishaela R Rubin, David W Dempster, James Sliney Jr., Hua Zhou, Thomas L Nickolas, Emily M Stein, Elzbieta Dworakowski, Maryann Dellabadia, Rebecca Ives, Donald J McMahon, Chiyuan Zhang, Shonni J Silverberg, Elizabeth Shane, Serge Cremers, John P Bilezikian

Teriparatide increases bone mineral density in a man with osteoporosis pseudoglioma
Henrique Pierotti Arantes, Elizabete Ribeiro Barros, Ilda Kunii, John P Bilezikian, Marise Lazaretti‐Castro

Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting
Verónica Alonso, Clara E Magyar, Bin Wang, Alessandro Bisello, Peter A Friedman

 

Vitamin D Articles 2009 - Present

 

Effects of 25-hydroxyvitamin D3 on proliferation and osteoblast differentiation of human marrow stromal cells require CYP27B1/1α-hydroxylase
Shuo Geng, Shuanhu Zhou and Julie Glowacki

The vitamin D analogue 2MD increases bone turnover but not BMD in postmenopausal women with osteopenia: Results of a 1-year phase 2 double-blind, placebo-controlled, randomized clinical trial
Hector F DeLuca, Wendy Bedale, Neil Binkley, J Chris Gallagher, Michael Bolognese, Munro Peacock, John Aloia, Margaret Clagett-Dame and Lori Plum

Why the IOM recommendations for vitamin D are deficient
Robert P Heaney and Michael F Holick

Evidence-based policy on dietary calcium and vitamin D
Ian R Reid and Alison Avenell

The effects of whole-body vibration training and vitamin D supplementation on muscle strength, muscle mass, and bone density in institutionalized elderly women: A 6-month randomized, controlled trial
Sabine MP Verschueren, An Bogaerts, Christophe Delecluse, Albrecht L Claessens, Patrick Haentjens, Dirk Vanderschueren and Steven Boonen

Impact of race on hyperparathyroidism, mineral disarrays, administered vitamin D mimetic, and survival in hemodialysis patients
Kamyar Kalantar-Zadeh, Jessica E Miller, Csaba P Kovesdy, Rajnish Mehrotra, Lilia R Lukowsky, Elani Streja, Joni Ricks, Jennie Jing, Allen R Nissenson, Sander Greenland and Keith C Norris

Cross-sectional association between serum vitamin D concentration and walking speed measured at usual and fast pace among older women: The EPIDOS study
Cédric Annweiler, Anne-Marie Schott, Manuel Montero-Odasso, Gilles Berrut, Bruno Fantino, François R Herrmann and Olivier Beauchet

Leptin stimulates fibroblast growth factor 23 expression in bone and suppresses renal 1α,25-dihydroxyvitamin D3 synthesis in leptin-deficient ob/ob Mice
Kiyomi Tsuji, Toyonobu Maeda, Tetsuya Kawane, Ayako Matsunuma and Noboru Horiuchi

The calcium-sensing receptor and 25-hydroxyvitamin D–1α-hydroxylase interact to modulate skeletal growth and bone turnover
Christian Richard, Rujuan Huo, Rana Samadfam, Isabel Bolivar, Dengshun Miao, Edward M Brown, Geoffrey N Hendy and David Goltzman

Effect of vitamin D3 and calcium on fracture risk in 65- to 71-year-old women: A population-based 3-year randomized, controlled trial—the OSTPRE-FPS
Kari Salovaara, Marjo Tuppurainen, Matti Kärkkäinen, Toni Rikkonen, Lorenzo Sandini, Joonas Sirola, Risto Honkanen, Esko Alhava and Heikki Kröger

A patient with severe hypercalcemia in multiple organ dysfunction syndrome: Role of elevated circulating 1α,25(OH)2vitamin D levels
Junichiro James Kazama, Takashi Yamamoto, Hiroshi Oya, Satoshi Yamamoto, Yoshinobu Sato, Junko Sakurada, Tadayuki Honda, Hiroshi Endoh and Ichiei Narita

Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats
Akishige Hokugo, Russell Christensen, Evelyn M Chung, Eric C Sung, Alan L Felsenfeld, James W Sayre, Neal Garrett, John S Adams and Ichiro Nishimura

A nonsecosteroidal vitamin D receptor ligand with improved therapeutic window of bone efficacy over hypercalcemia
Masahiko Sato, Jianliang Lu, Stephen Iturria, Keith R Stayrook, Lorri L Burris, Qing Qiang Zeng, Allen Schmidt, Robert J Barr, Chahrzad Montrose-Rafizadeh, Henry U Bryant and Yanfei L Ma

CDP/cut is an osteoblastic coactivator of the vitamin D receptor (VDR)
Eiji Ochiai, Hirochika Kitagawa, Ichiro Takada, Sally Fujiyama, Shun Sawatsubashi, Mi-sun Kim, Yoshihiro Mezaki, Yu Tsushima, Ken-ichiro Takagi, Yoshiaki Azuma, Ken-ichi Takeyama, Kazuyoshi Yamaoka, Shigeaki Kato and Takashi Kamimura

Taking vitamin D with the largest meal improves absorption and results in higher serum levels of 25-hydroxyvitamin D
Guy B Mulligan and Angelo Licata

Persistent secondary hyperparathyroidism and vertebral fractures in kidney transplantation: Role of calcium-sensing receptor polymorphisms and vitamin D deficiency
Sandro Giannini, Stefania Sella, Fatima Silva Netto, Catia Cattelan, Luca Dalle Carbonare, Roberta Lazzarin, Francesco Marchini, Paolo Rigotti, Claudio Marcocci, Filomena Cetani, Elena Pardi, Angela D'Angelo, Giuseppe Realdi and Luciana Bonfante

Elevated vitamin D receptor levels in genetic hypercalciuric stone-forming rats are associated with downregulation of Snail
Shaochun Bai, Hongwei Wang, Jikun Shen, Randal Zhou, David A Bushinsky and Murray J Favus

Serum 25-hydroxyvitamin D and the risk of hip and nonspine fractures in older men
Jane A Cauley, Neeta Parimi, Kristine E Ensrud, Douglas C Bauer, Peggy M Cawthon, Steven R Cummings, Andrew R Hoffman, James M Shikany, Elizabeth Barrett-Connor and Eric Orwoll

Serum 25-hydroxyvitamin D levels modulate the acute-phase response associated with the first nitrogen-containing bisphosphonate infusion
Francesco Bertoldo, Serena Pancheri, Sonia Zenari, Stefania Boldini, Benedetta Giovanazzi, Mirko Zanatta, Maria Teresa Valenti, Luca Dalle Carbonare and Vincenzo Lo Cascio

Vitamin D receptor (VDR) gene polymorphism is associated with left ventricular (LV) mass and predicts left ventricular hypertrophy (LVH) progression in end-stage renal disease (ESRD) patients
Alessandra Testa, Francesca Mallamaci, Francesco A Benedetto, Anna Pisano, Giovanni Tripepi, Lorenzo Malatino, Ravi Thadhani and Carmine Zoccali

Bone mineralization defects and vitamin D deficiency: Histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients
Matthias Priemel, Christoph von Domarus, Till Orla Klatte, Steffen Kessler, Julia Schlie, Simon Meier, Nils Proksch, Frederic Pastor, Clemens Netter, Thomas Streichert, Klaus Püschel and Michael Amling

Low maternal vitamin D status and fetal bone development: Cohort study
Pamela Mahon, Nicholas Harvey, Sarah Crozier, Hazel Inskip, Sian Robinson, Nigel Arden, Rama Swaminathan, Cyrus Cooper and Keith Godfrey

Vitamin D insufficiency and skeletal development in utero
Martin Hewison and John S Adams

Effects of hPTH(1-34) Infusion on Circulating Serum Phosphate, 1,25-Dihydroxyvitamin D, and FGF23 Levels in Healthy Men
Sherri-Ann M Burnett-Bowie, Maria P Henao, Melissa E Dere, Hang Lee and Benjamin Z Leder

1α,25(OH)2 Vitamin D3 Induction of ATP Secretion in Osteoblasts
Payal Biswas and Laura P Zanello

Dietary Calcium and Serum 25-Hydroxyvitamin D Status in Relation to BMD Among U.S. Adults
Heike A Bischoff-Ferrari, Douglas P Kiel, Bess Dawson-Hughes, John E Orav, Ruifeng Li, Donna Spiegelman, Thomas Dietrich and Walter C Willett

Vitamin D Status, Parathyroid Function, Bone Turnover, and BMD in Postmenopausal Women With Osteoporosis: Global Perspective
Natalia O Kuchuk, Natasja M van Schoor, Saskia M Pluijm, Arkadi Chines and Paul Lips

Compound Heterozygous Mutations in the Vitamin D Receptor in a Patient With Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets With Alopecia
Yulin Zhou, Jining Wang, Peter J Malloy, Zdenek Dolezel and David Feldman

Wintertime Vitamin D Supplementation Inhibits Seasonal Variation of Calcitropic Hormones and Maintains Bone Turnover in Healthy Men
Heli T Viljakainen, Milja Väisänen, Virpi Kemi, Toni Rikkonen, Heikki Kröger, E Kalevi A Laitinen, Hannu Rita and Christel Lamberg-Allardt

Analysis of CYP27B1, Encoding 25-Hydroxyvitamin D-1α-Hydroxylase, as a Candidate Tumor Suppressor Gene in Primary and Severe Secondary/Tertiary Hyperparathyroidism
Kelly Lauter and Andrew Arnold

Vitamin D–Independent Therapeutic Effects of Extracellular Calcium in a Mouse Model of Adult-Onset Secondary Hyperparathyroidism
Karin Weber, Ute Zeitz, Claudia Bergow, Sieglinde Hirmer, Christiane Schüler and Reinhold G Erben

Basic Research Perspectives


Vitamin D and Health: Perspectives From Mice and Man
Roger Bouillon, Heike Bischoff-Ferrari, and Walter Willett

Review of Nonprimate, Large Animal Models for
Osteoporosis Research
Susan Reinwald and David Burr

Where Wnts Went: The Exploding Field of Lrp5 and Lrp6
Signaling in Bone
Bart O Williams and Karl L Insogna

Role of the Osteoblast Lineage in the Bone Marrow
Hematopoietic Niches
Joy Y. Wu, David T. Scadden, and Henry M. Kronenberg

Osteoclasts and Arthritis
Georg Schett and Steven L. Teitelbaum

Regulation of Osteogenesis-Angiogenesis Coupling
by HIFs and VEGF
Ernestina Schipani, Christa Maes, Geert Carmeliet, and Gregg L. Semenza

Spatiotemporal Delivery Strategies for Promoting Musculoskeletal
Tissue Regeneration
Robert E. Guldberg

Myeloma Bone Disease
Ralph D. Sanderson and Joshua Epstein

Future of Osteoporosis Genetics: Enhancing Genome-Wide Association Studies
Charles R. Farber and Aldons J. Lusis

Of mice and (wo)men: Mouse models of breast cancer metastasis to bone
Robert H. Goldstein, Robert A. Weinberg and Michael Rosenblatt

Role of the Osteoblast Lineage in the Bone Marrow Hematopoietic Niches
Joy Y. Wu, David T. Scadden and Henry M. Kronenberg

Guidelines for assessment of bone microstructure in rodents using micro–computed tomography
Mary L. Bouxsein, Stephen K. Boyd, Blaine A. Christiansen, Robert E. Guldberg, Karl J. Jepsen, and Ralph Müller

Gr-1+CD11b+ myeloid-derived suppressor cells: Formidable partners in tumor metastasis
Li Yang, Claire M. Edwards, Gregory R. Mundy

Sclerostin: A gem from the genome leads to bone-building antibodies
Chris Paszty, Charles H. Turner and Martyn K. Robinson

FGF-23: More than a regulator of renal phosphate handling?
Harald Jüppner, Myles Wolf and Isidro B. Salusky

IGF-1 and bone: New discoveries from mouse models
Shoshana Yakar, Hayden-William Courtland and David Clemmons 

Osteosarcoma
Richard Gorlick and Chand Khanna

The amazing osteocyte
Lynda F Bonewald

The osteoblast: An insulin target cell controlling glucose homeostasis
Thomas L Clemens and Gerard Karsenty

FoxO1: A molecule for all seasons
Stavroula Kousteni

Genome-scale techniques highlight the epigenome and redefine fundamental principles of gene regulation
J Wesley Pike

Circulating osteogenic cells: Implications for injury, repair, and regeneration
Robert J Pignolo and Moustapha Kassem

Clinical Perspectives


Considerations for Development of Surrogate Endpoints for
Antifracture Efficacy of New Treatments in Osteoporosis:
A Perspective
Mary L Bouxsein and Pierre D Delmas

Theoretical Implications of the Biomechanical Fracture Threshold
Tony M Keaveny and Mary L Bouxsein

Bridging the Osteoporosis Quality Chasm
Jeffrey R Curtis, Jonathan D Adachi, and Kenneth G Saag

Assessing the Clinical Utility of Serum CTX in Postmenopausal
Osteoporosis and Its Use in Predicting Risk of
Osteonecrosis of the Jaw
Sanford Baim and Paul D Miller

FRAX Facts
Nelson B. Watts, Bruce Ettinger, and Meryl S. LeBoff 

Clinical Value of Monitoring BMD in Patients Treated With
Bisphosphonates for Osteoporosis
Nelson B. Watts, E. Michael Lewiecki, Sydney L. Bonnick, Andrew J. Laster, Neil Binkley, Robert D. Blank,
Piet P. Geusens, Paul D. Miller, Steven M. Petak, Robert R. Recker, Kenneth G. Saag, John Schousboe,
Ethel S. Siris, and John P. Bilezikian

Following BMD in Patients on Bisphosphonates: Another Perspective
Robert A. Adler and Murray J. Favus

Atrial fibrillation and bisphosphonate therapy
Michael Pazianas, Juliet Compston and Christopher L. Huang

Atypical subtrochanteric and diaphyseal femoral fractures: Report of a Task Force of the American Society for Bone and Mineral Research
lElizabeth Shane, David Burr, Peter R. Ebeling, Bo Abrahamsen, Robert A. Adler, Thomas D. Brown, Angela M. Cheung, Felicia Cosman, Jeffrey R. Curtis, Richard Dell, David Dempster, Thomas A. Einhorn, Harry K. Genant, Piet Geusens, Klaus Klaushofer, Kenneth Koval, Joseph M. Lane, Fergus McKiernan, Ross McKinney, Alvin Ng, Jeri Nieves, Regis O'Keefe, Socrates Papapoulos, Howe Tet Sen, Marjolein CH van der Meulen, Robert S. Weinstein and Michael Whyte 

The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: Is a revision needed?
Sundeep Khosla, L Joseph Melton III and B Lawrence Riggs

Evidence-based policy on dietary calcium and vitamin D
Ian R Reid and Alison Avenell

Why the IOM recommendations for vitamin D are deficient
Robert P Heaney and Michael F Holick

A clinician's guide to X-linked hypophosphatemia
Thomas O Carpenter, Erik A Imel, Ingrid A Holm, Suzanne M Jan de Beur and Karl L Insogna

Uncertainties in the prevention and treatment of glucocorticoid-induced osteoporosis
Karen E Hansen, H Alexander Wilson, Carol Zapalowski, Howard A Fink, Salvatore Minisola and Robert A Adler

Hypoparathyroidism in the adult: Epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research
John P Bilezikian, Aliya Khan, John T Potts Jr, Maria Luisa Brandi, Bart L Clarke, Dolores Shoback, Harald Jüppner, Pierre D'Amour, John Fox, Lars Rejnmark, Leif Mosekilde, Mishaela R Rubin, David Dempster, Rachel Gafni, Michael T Collins, Jim Sliney and James Sanders

Forum on aging and skeletal health: Summary of the proceedings of an ASBMR workshop
Sundeep Khosla, Teresita M Bellido, Marc K Drezner, Catherine M Gordon, Tamara B Harris, Douglas P Kiel, Barbara E Kream, Meryl S LeBoff, Jane B Lian, Charlotte A Peterson, Clifford J Rosen, John P Williams, Karen K Winer and Sherry S Sherman

Obesity and fracture in men and women: An epidemiologic perspective
Carrie M Nielson, Priya Srikanth and Eric S Orwoll

Readers’ Choice Articles

The Editors are pleased to present a new Virtual Issue comprised of the 20 most frequently downloaded and cited JBMR articles from the last two years. In effect, this Virtual Issue is a collection of "readers’ choice" articles that highlight the best and the most relevant of late in the JBMR. We hope you find it interesting and helpful.


Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates
Ana O. Hoff, Bela B. Toth, Kadri Altundag, Marcella M. Johnson, Carla L. Warneke, Mimi Hu, Ajay Nooka, Gilbert Sayegh, Valentina Guarneri, Kimberly Desrouleaux, Jeffrey Cui, Andrea Adamus, Robert F. Gagel and Gabriel N. Hortobagyi

Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
Xiodong Li, Michael S. Ominsky, Qing-Tian Niu, Ning Sun, Betsy Daugherty, Diane D'Agostin, Carole Kurahara, Yongming Gao, Jin Cao, Jianhua Gong, Frank Asuncion, Mauricio Barrero, Kelly Warmington, Denise Dwyer, Marina Stolina, Sean Morony, Ildiko Sarosi, Paul J. Kostenuik, David L. Lacey, Scott W. Simonet, Hua Zhu Ke and Chris Paszty

A population-based assessment of rates of bone loss at multiple skeletal sites: Evidence for substantial trabecular bone loss in young adult women and men
Lawrence B. Riggs, Joseph L. Melton III, Richard A. Robb, Jon J. Camp, Elizabeth J. Atkinson, Lisa McDaniel, Shreyasee Amin, Peggy A. Rouleau and Sundeep Khosla

Histomorphometric and mu CT analysis of bone biopsies from postmenopausal osteoporotic women treated with strontium ranelate
Monique E. Arlot, Yebin Jiang, Harry K. Genant, Jenny Zhao, Brigitte Burt-Pichat, Jean-Paul Roux, Pierre D. Delmas, and Pierre J. Meunier

Correlation of obesity and osteoporosis: Effect of fat mass on the determination of osteoporosis
Lan-Juan Zhao, Hui Jiang, Christopher J. Papasian, Dev Maulik, Betty Drees, James Hamilton and Hong-Wen Deng

Finite element analysis based on in vivo HR-pQCT images of the distal radius is associated with wrist fracture in postmenopausal women
Stephanie Boutroy, Bert Van Rietbergen, Elisabeth Sornay-Rendu, Francoise Munoz, Mary L. Bouxsein and Pierre D. Delmas

Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, and Active-Controlled Clinical Trial
Stuart L. Silverman, Claus Christiansen, Harry K. Genant, Slobodan Vukicevic, Jose R. Zanchetta, Tobie J. de Villiers, Ginger Constantine and Arkadi Chines

Comparison of the Effect of Denosumab and Alendronate on BMD and Biochemical Markers of Bone Turnover in Postmenopausal Women With Low Bone Mass: A Randomized, Blinded, Phase 3 Trial
Jacques P. Brown, Richard L. Prince, Chad Deal, Robert R. Recker, Douglas P. Kiel, Luiz H. de Gregorio, Peyman Hadji, Lorenz C. Hofbauer, Jose M. Alvaro-Gracia, Huei Wang, Matthew Austin, Rachel B. Wagman, Richard Newmark, Cesar Libanati, Javier San Martin and Henry G. Bone

Effects of bazedoxifene on BMD and bone turnover in postmenopausal women: 2-yr results of a randomized, double-blind, placebo-, and active-controlled study
Paul D. Miller, Arkadi A. Chines, Claus Christiansen, Hans C. Hoeck, David L. Kendler, Michael E. Lewiecki, Grattan Woodson, Amy B. Levine, Ginger Constantine and Pierre D. Delmas

Effects of intravenous zoledronic acid once yearly on bone remodeling and bone structure
Robert R. Recker, Pierre D. Delmas, Johan Halse, Ian R. Reid, Steven Boonen, Pedro A. Garcia-Hernandez, Jerzy Supronik, Michael E. Lewiecki, Luis Ochoa, Paul Miller, Huilin Hu, Peter Mesenbrink,Florian Hartl, Juerg Gasser and Erik F. Eriksen

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis
Xiaodong Li, Michael S. Ominsky, Kelly S. Warmington, Sean Morony, Jianhua Gong, Jin Cao, Yongming Gao, Victoria Shalhoub, Barbara Tipton, R.J. Haldankar, Qing Chen, Aaron Winters, Tom Boone, Zhaopo Geng, Qing-Tian Niu, Hua Zhu Ke, Paul J. Kostenuik, W. Scott Simonet, David L. Lacey and Chris Paszty

Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23
Yuji Yamazaki, Taro Tamada, Noriyuki Kasai, Itaru Urakawa, Yukiko Aono, Hisashi Hasegawa, Toshiro Fujita, Ryota Kuroki, Takeyoshi Yamashita, Seiji Fukumoto and Takashi Shimada

Osteogenic differentiation of human adipose tissue-derived stem cells is modulated by the miR-26a targeting of the SMAD1 transcription factor
Ettore Luzi, Francesca Marini, Silvia Carbonell Sala, Isabella Tognarini, Gianna Galli, Maria Luisa Brandi and Maria Luisa

Activation of beta-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult beta-Catenin Conditional Activation Mice
Mei Zhu, Dezhi Tang, Qiuqian Wu, Suyang Hao, Mo Chen, Chao Xie, Randy N. Rosier, Regis J. O'Keefe, Michael Zuscik and Di Chen

EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts
Elizabeth H. Allan, Karl D. Hausler, Tao Wei, Jonathan H. Gooi, Julian M. W. Quinn, Blessing Crimeen-Irwin, Sueli Pompolo, Natalie A. Sims, Matthew T. Gillespie, Jude E. Onyia and John T. Martin

Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro
Hua Wang, Yuji Yoshiko, Ryoko Yamamoto, Tomoko Minamizaki, Katsuyuki Kozai, Kazua Tanne, Jane Aubin, and Norihiki Maeda

Strontium ranelate reduces the risk of vertebral fractures in patients with osteopenia
Ego Seeman, Jean-Pierre Devogelaer, Roman Loren, Timothy Spector, Kim Brixen, Adam Balogh, Gerold Stucki, and Jean-Yves Reginster

Vitamin D and health: Perspectives from mice and man
Roger Bouillon, Heike Bischoff-Ferrari and Walter Willett

Older men with low serum estradiol and high serum SHBG have an increased risk of fractures
Dan Mellstroem, Liesbeth Vandenput, Hans Mallmin, Anna H. Holmberg, Mattias Lorentzon, Anders Oden, Helena Johansson, Eric S. Orwoll, Fernand Labrie, Magnus K. Karlsson, Osten Ljunggren and Claes Ohlsson

Enzyme replacement therapy for murine hypophosphatasia
Jose Luis Millan, Sonoko Narisawa, Isabelle Lemire, Thomas P. Loisel, Guy Boileau, Pierre Leonard, Svetlana Gramatikova, Robert Terkeltaub, Nancy Pleshko Camacho, Marc D. McKee, Philippe Crine and Michael P. Whyte
 

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